Bioidentical compounds are substances that are chemically identical to those that naturally occur in the human body. These compounds are often used in hormone replacement therapy (HRT) to mimic natural hormones such as estrogen, progesterone, and testosterone. The use of bioidentical hormones has gained popularity due to the belief that they offer a more "natural" approach compared to synthetic hormones. However, their safety and efficacy remain subjects of considerable debate within the field of toxicology.