In the field of toxicology, hematoxylin and eosin (H&E) are crucial dyes used for staining tissue samples. Hematoxylin is a naturally occurring dye that stains cell nuclei a deep blue to purple, while eosin is a synthetic dye that stains the cytoplasm and extracellular matrix in shades of pink and red. Together, they provide a clear contrast that helps in the microscopic examination of tissue morphology and pathology.