Metalloproteinases are a group of enzymes that require metal ions to function. These enzymes play critical roles in the degradation of extracellular matrix (ECM) components, thereby influencing various biological processes including tissue remodeling, inflammation, and cell migration. They are categorized mainly into matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinase (ADAM) family, each with distinct structural and functional properties.
