In the field of Toxicology, partition coefficients play a critical role in understanding how chemicals distribute themselves between different phases, typically between water and a non-aqueous phase like octanol. The partition coefficient (often expressed as log P) is a ratio that indicates how a compound divides between these two immiscible solvents. This ratio is crucial for predicting the absorption, distribution, metabolism, and excretion (ADME) of a compound in biological systems.