The Joint FAO/WHO Expert Committee on Food Additives (JECFA) has established an acceptable daily intake (ADI) for aspartame, which indirectly limits aspartate consumption. The ADI is set at 40 mg/kg body weight per day. This level is considered safe for the general population, excluding individuals with phenylketonuria (PKU), a genetic disorder that affects the metabolism of phenylalanine, one of the breakdown products of aspartame.
