Several substances are frequently discussed in the context of the gateway hypothesis:
Nicotine: Often considered a gateway drug due to its high potential for addiction and its role in leading users, particularly adolescents, to try other substances. Alcohol: Widely available and socially accepted, alcohol can lower inhibitions and increase the likelihood of experimenting with other drugs. Cannabis: Although its status as a gateway drug is debated, some studies suggest that early cannabis use might contribute to the use of other illegal drugs.