What are Some Examples of Signal Transduction in Toxicology?
Several examples illustrate the impact of toxicants on signal transduction:
Endocrine Disruptors: Chemicals like bisphenol A can bind to hormone receptors, altering normal endocrine signaling and potentially leading to reproductive and developmental issues. Carcinogens: Many carcinogens disrupt normal signaling pathways, such as those involving the p53 protein, leading to unchecked cell division and tumor formation. Neurotoxins: Compounds like lead interfere with neurotransmitter signaling pathways, resulting in neurodevelopmental disorders.