What are the Challenges in Developing Toxicity Models?
Despite their utility, toxicity models face several challenges:
Data Availability and Quality: Reliable predictions require high-quality data, which is often unavailable or inconsistent. Complexity of Biological Systems: Accurately modeling the interactions within a biological system can be highly complex, given the vast number of variables involved. Model Validation: Ensuring the accuracy and reliability of a model is crucial yet challenging, requiring rigorous validation against experimental data. Regulatory Acceptance: For a model to be widely used, it must be accepted by regulatory bodies, which often have stringent requirements.
