What are the Challenges in Implementing Weight of Evidence?
One of the main challenges in implementing WoE is the subjective nature of weighing different types of evidence. Different experts might assign different levels of importance to certain data sets based on their own interpretations and experiences. Additionally, the quality and availability of data can vary, which may lead to inconsistencies in the overall assessment. There is also the challenge of integrating diverse types of data, such as combining results from in vitro tests with epidemiological studies, which may have different endpoints and methodologies.