complexity of mixtures

What Are the Challenges in Mixture Toxicology?

One major challenge is the sheer number of possible combinations of chemicals and their potential interactions. Additionally, the variability in exposure levels and durations further complicates the assessment. Another challenge is the limited data on the toxicological profiles of many chemicals, particularly when they occur in mixtures. Moreover, regulatory frameworks are often designed for single chemicals, making it difficult to apply them to mixtures.

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