What are the Clinical Applications of Idarucizumab?
Clinically, idarucizumab is used in two primary scenarios: in cases of life-threatening or uncontrolled bleeding in patients taking dabigatran, and when urgent surgery or invasive procedures are required. The FDA approved idarucizumab under accelerated approval pathways due to its significant benefit in these critical situations. It has become a standard treatment in emergency departments and surgical settings where rapid anticoagulation reversal is necessary.