What are the Common Histological Techniques Used in Toxicology?
In toxicology, several histological techniques are routinely used:
Light Microscopy: This is the most basic technique, allowing for the examination of stained tissue sections. Electron Microscopy: Provides detailed images at the ultrastructural level, useful for identifying sub-cellular damage. Immunohistochemistry (IHC): Utilizes antibodies to detect specific proteins, providing insights into changes in protein expression caused by toxicants. In situ Hybridization: Allows for the visualization of specific nucleic acid sequences within tissue sections, helping identify changes in gene expression.
