What are the Common Toxic Agents Causing Axonal Degeneration?
Several toxic substances are known to cause axonal degeneration. Lead is a well-known neurotoxin that can disrupt synaptic function and induce axonal damage. Organophosphates, commonly found in pesticides, inhibit acetylcholinesterase, leading to continuous nerve stimulation and subsequent axonal injury. Acrylamide, used in industrial processes, is another compound that can cause axonal degeneration by interfering with cytoskeletal proteins.
