Hepatotoxicity: Damage to the liver, often caused by drugs like acetaminophen. Neurotoxicity: Harm to the nervous system, which can be induced by heavy metals like lead and mercury. Nephrotoxicity: Kidney damage, which can result from exposure to substances like nonsteroidal anti-inflammatory drugs (NSAIDs). Cardiotoxicity: Effects on the heart, potentially caused by chemotherapy agents. Carcinogenicity: The potential to cause cancer, as seen with prolonged exposure to tobacco smoke.