What Are the Consequences of Nuclear Lamina Disruption?
Alterations in the nuclear lamina can have several detrimental effects. For instance, disruption of the lamina can lead to genomic instability, a hallmark of cancer. Furthermore, it can affect the cell's ability to properly regulate gene expression, leading to aberrant cellular behavior and disease. In the context of toxicology, understanding these consequences can help identify the potential long-term impacts of exposure to harmful substances.
