There are several types of SOD, each with distinct metal cofactors and subcellular locations. The three main types are:
Copper-Zinc SOD (Cu,Zn-SOD): Predominantly found in the cytosol. Manganese SOD (Mn-SOD): Located in the mitochondria, where it protects against mitochondrial oxidative damage. Extracellular SOD (EC-SOD): Found in extracellular fluids and tissues, playing a role in protecting the extracellular matrix from oxidative stress.
