What are the Health Risks Associated with Heterocyclic Amines?
Exposure to HCAs has been linked to several health risks. Epidemiological studies have correlated high intake of HCAs with increased incidence of colorectal, breast, prostate, and pancreatic cancers. The mechanism of action involves the metabolic activation of HCAs by liver enzymes into compounds that can bind to DNA, causing mutations and potentially leading to cancer over time.
