What are the implications of CYP2E1 in drug interactions?
CYP2E1 is a key player in drug-drug interactions, particularly when multiple substrates or inhibitors are present. For example, concurrent use of alcohol and acetaminophen can lead to competitive inhibition and increased production of toxic metabolites. Understanding the role of CYP2E1 in such interactions helps in predicting potential adverse effects and guiding safer medication practices.
