What Are the Limitations of Cell Culture in Toxicology?
While cell culture techniques offer numerous benefits, they also have limitations. One significant challenge is the lack of in vivo context. Cells in culture do not fully replicate the complex interactions and signaling pathways present in living organisms. Additionally, cell cultures may not accurately represent the genetic diversity found in human populations, potentially limiting the applicability of findings. Furthermore, the artificial conditions of cell culture can sometimes lead to alterations in cell behavior.
