ed50

What are the Limitations of ED50?

While ED50 is a valuable tool, it has limitations:
Population Variability: ED50 does not account for differences in individual susceptibility, such as age, gender, or genetic factors.
Complex Interactions: It assumes a single mode of action and may not account for synergistic or antagonistic interactions with other substances.
Non-Linear Effects: Some substances may exhibit non-linear dose-response relationships, making ED50 less reliable.

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