Despite their utility, screening tests have some limitations:
1. False Positives/Negatives: Screening tests can sometimes yield false positive or false negative results, necessitating confirmatory testing. 2. Limited Scope: Not all toxic substances can be detected by a single screening test, requiring multiple tests for comprehensive screening. 3. Sensitivity and Specificity: While highly sensitive, these tests may lack specificity, leading to cross-reactivity with other substances. 4. Sample Quality: The accuracy of the test can be affected by the quality and handling of the sample.
