What Are the Mechanisms Behind Toxin-Induced Anemia?
Toxin-induced anemia can occur through various mechanisms:
Hemolysis: Toxins such as arsenic cause oxidative damage to RBCs, leading to premature destruction. Bone Marrow Suppression: Substances like benzene can suppress or damage the bone marrow, reducing RBC production. Inhibition of Hemoglobin Synthesis:Lead disrupts enzymes necessary for hemoglobin synthesis, resulting in inadequate formation of RBCs. Impaired Oxygen Transport:Carbon monoxide competes with oxygen for binding sites on hemoglobin, resulting in decreased oxygen delivery to tissues.
