The primary mechanism through which carnitine deficiency impacts toxicology is by impairing fatty acid oxidation. This impairment can lead to an accumulation of toxic fatty acid metabolites, which can have detrimental effects on organs such as the heart, liver, and kidneys. Moreover, carnitine is involved in the conjugation reaction, a detoxification pathway that converts lipophilic toxins into more water-soluble forms for excretion.
