What are the Potential Toxic Effects of Thioguanine?
While effective as a chemotherapeutic agent, thioguanine can cause a range of toxic effects. The most notable is myelosuppression, leading to decreased production of blood cells and increased risk of infections, anemia, and bleeding. Hepatotoxicity is another concern, with potential for liver damage marked by elevated liver enzymes and, in severe cases, veno-occlusive disease. Gastrointestinal toxicity, including nausea and vomiting, is also common.
