What are the Protective Mechanisms Against Excitotoxicity?
The body has several protective mechanisms to prevent excitotoxicity, including the regulation of glutamate release and reuptake, as well as the presence of antioxidants that mitigate oxidative stress. However, when these mechanisms are overwhelmed, such as in the case of acute exposure to neurotoxins, they may fail to protect neurons from excitotoxic damage.
