Symptoms of ANS toxicity can vary depending on whether the sympathetic or parasympathetic pathways are affected. Sympathetic overactivity might lead to symptoms such as increased heart rate, hypertension, and dilated pupils. In contrast, parasympathetic overactivity might cause bradycardia, hypotension, and miosis (constricted pupils). In severe cases, ANS disruption can lead to life-threatening conditions like respiratory failure.