What are the toxicological concerns associated with dexrazoxane?
While dexrazoxane is beneficial in reducing cardiac toxicity, its use is not without concerns. There have been discussions around its potential to induce secondary malignancies, particularly in pediatric patients. Some studies have suggested an increased risk of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) in children treated with dexrazoxane. However, these findings are still under debate, and ongoing research is needed to fully understand these risks.
