What Are the Toxicological Risks of CNS Stimulation?
One of the primary concerns in toxicology is the dose-response relationship. At therapeutic doses, many CNS stimulants can be beneficial. However, at higher doses, they may become toxic. High doses of stimulants like amphetamines and cocaine can lead to cardiovascular complications, hyperthermia, and even neurotoxicity. The risk of overdose is particularly high with illicit substances due to their unpredictable purity and strength.