What are the Treatment Options for Anticoagulant Toxicity?
Treatment of anticoagulant toxicity aims to reverse anticoagulation and manage bleeding. For warfarin, vitamin K is the antidote, while fresh frozen plasma or prothrombin complex concentrates may be required for severe cases. Protamine sulfate is used to reverse heparin effects. Specific reversal agents, such as idarucizumab for dabigatran and andexanet alfa for factor Xa inhibitors, are available for NOACs.
