There are several types of binding sites relevant to toxicology:
- Enzyme Active Sites: Toxins can inhibit enzymes by binding to their active sites, disrupting normal metabolic pathways. - Receptor Sites: Toxins may mimic or block endogenous ligands at receptor sites, altering cellular signaling pathways. - Transporter Sites: Binding to transporter proteins can affect the uptake and distribution of nutrients and ions. - DNA Binding Sites: Certain toxins can bind to DNA, causing mutations or disrupting replication and transcription processes.
