The exact mechanisms through which drugs induce lupus-like symptoms are not fully understood, but it is believed that certain medications can trigger an immune response in genetically predisposed individuals. Some of the most commonly implicated drugs include hydralazine, procainamide, and isoniazid. Others, like minocycline and quinidine, have also been reported to cause DIL. The risk factors include a higher dose and longer duration of drug exposure, as well as certain genetic markers.
