Several factors can induce phototoxic reactions. These include exposure to certain drugs, chemicals, and even some plant derivatives known as photosensitizers. Photosensitizers absorb UV light and subsequently release energy, leading to cellular damage. Common phototoxic agents include antibiotics like tetracyclines, non-steroidal anti-inflammatory drugs (NSAIDs), and some antifungal agents. Additionally, certain perfumes and cosmetics contain compounds that can trigger phototoxicity.