Policy changes in toxicology are primarily driven by advancements in scientific research, public health concerns, and technological innovations. As researchers uncover new information about the adverse health effects of chemicals and pollutants, regulatory bodies must update existing guidelines to reflect these findings. Additionally, heightened public awareness and advocacy for environmental protection have pressured policymakers to adopt more stringent standards. The development of new technologies, such as alternative testing methods and analytical tools, also enables more accurate assessments of chemical safety, prompting updates to regulatory frameworks.