Several factors can influence the lethality of a substance, including:
- Route of Exposure: The way a substance enters the body (oral, inhalation, dermal) can affect its toxicity. - Species Differences: Different species may react differently to the same substance due to variations in metabolism, absorption, and elimination. - Age and Sex: Age and sex of the test subjects can also play a role; for example, young or elderly individuals may be more susceptible. - Health Status: Pre-existing health conditions can alter how a substance affects an organism.