What Factors Influence the Activity of Detoxification Enzymes?
Several factors can modulate the function of detoxification enzymes, including:
Diet: Nutrients and certain foods can induce or inhibit enzyme activity. For example, cruciferous vegetables like broccoli can enhance Phase II enzyme activity. Age: Enzyme activity can decline with age, affecting detoxification efficiency. Health status: Conditions such as liver disease can impair enzyme function. Exposure to other substances: Concurrent exposure to multiple toxins can affect enzyme activity through competitive inhibition or other mechanisms.