Several factors can influence how a biological system responds to a toxicant:
Dosage: The dose-response relationship is a fundamental concept in toxicology. Generally, higher doses lead to more severe responses. Exposure Route: The route of exposure (ingestion, inhalation, dermal) can significantly impact the type and severity of the response. Individual Differences: Genetic makeup, age, sex, and health status can all affect an individual's susceptibility to toxicants. Chemical Form: The chemical nature of the toxicant, including its solubility and stability, plays a crucial role in its toxicological profile. Synergistic Effects: The presence of other chemicals can modify the toxic response, sometimes leading to unexpected outcomes.
