What Impact Do Concentration Gradients Have on Toxicant Metabolism?
Metabolism of toxicants, primarily occurring in the liver, is also influenced by concentration gradients. Metabolic enzymes can transform lipophilic toxicants into more water-soluble forms, facilitating their excretion. The concentration gradient between the inside and outside of cells can affect the rate at which these metabolic processes occur, thereby impacting the duration and intensity of the toxicant's effects.
