Several interventions are utilized in the ICU setting to manage toxicological emergencies. Activated charcoal is often administered if the poisoning is recent, to bind toxins in the gastrointestinal tract and prevent absorption. Antidotes are given when available and appropriate, such as N-acetylcysteine for acetaminophen overdose. Supportive measures, including fluid therapy, vasopressors, and mechanical ventilation, are frequently employed to maintain hemodynamic stability and respiratory function.