In the field of toxicology, a dose-response relationship is a fundamental concept that describes how the magnitude of an organism's response varies with the amount of exposure to a substance. While traditionally, many studies have assumed a linear dose-response, where the effect is directly proportional to the dose, non-linear dose response refers to a relationship where this proportionality does not hold true. In such cases, small changes in dose can lead to disproportionately large or small changes in response.
