Cytokines are key mediators of inflammation. Pro-inflammatory cytokines like TNF-alpha, IL-1, and IL-6 are released in response to toxic insults and initiate the inflammatory process. This response is crucial in isolating and removing harmful agents. However, chronic exposure to toxins can lead to prolonged cytokine release, resulting in persistent inflammation and tissue damage. Conversely, anti-inflammatory cytokines, such as IL-10 and TGF-beta, work to resolve inflammation and repair tissues.
