What is the Role of DNA Methylation in Toxicology?
DNA methylation is a well-studied epigenetic mechanism, involving the addition of a methyl group to the DNA molecule, typically at cytosine bases. This modification can suppress gene expression and is often triggered by environmental factors, including toxins. Aberrant DNA methylation patterns have been linked to cancers, neurological disorders, and other chronic diseases, making it a crucial focus in toxicological research.