What is the Role of the Blood-Brain Barrier in Circulatory Toxicology?
The blood-brain barrier (BBB) is a selective barrier that protects the brain from potentially harmful substances in the bloodstream. In toxicology, the BBB is crucial because it limits the entry of neurotoxicants into the central nervous system. However, some lipophilic toxins and small molecules can cross the BBB, potentially leading to neurological damage.