What is the Role of Toxins in Clostridium perfringens Infections?
The major virulence factors of Clostridium perfringens are its toxins. These toxins disrupt cellular functions and cause tissue damage. For example, the alpha-toxin has phospholipase activity that destroys cell membranes, leading to cell death and tissue necrosis. Understanding these toxins' mechanisms is crucial for developing targeted therapies and preventive measures.
