The mechanisms of respiratory toxicity can be complex, involving diverse pathways:
Direct cellular damage: Toxicants can cause oxidative stress, inflammation, and cell death within the lung tissue. Immune response modulation: Some substances can alter immune responses, leading to hypersensitivity or autoimmune reactions in the respiratory system. Carcinogenesis: Repeated exposure to certain carcinogens can initiate and promote the development of cancerous cells within the respiratory tract.