Free radicals are implicated in the pathogenesis of numerous diseases. For example, in cardiovascular disease, oxidative stress can lead to the oxidation of low-density lipoproteins (LDL), contributing to atherosclerosis. In cancer, free radicals can cause mutations in DNA, potentially leading to the initiation and progression of cancerous cells. Neurodegenerative diseases like Alzheimer's and Parkinson's are also associated with oxidative damage to neuronal cells.