What Role Do Genetic Factors Play in Metabolic Disorders?
Genetic factors are often involved in metabolic disorders, especially those that are inherited. Genetic mutations can affect the function of enzymes involved in metabolic pathways. For instance, mutations in genes encoding for enzymes in lipid metabolism can lead to disorders like familial hypercholesterolemia. However, even in genetically predisposed individuals, exposure to certain toxins can exacerbate or trigger the manifestation of the disorder.