Governments establish regulatory frameworks and guidelines to manage chemical safety and protect public health. Agencies such as the Environmental Protection Agency (EPA) in the United States and the European Chemicals Agency (ECHA) in Europe are pivotal in setting standards for exposure limits, labeling requirements, and safety testing. Governments also fund toxicological research, which supports the development of new methods to assess chemical risks and improve public health outcomes. They have the power to enforce compliance through inspections and penalties, ensuring that corporations adhere to safety regulations.