What Role do Metabolic Enzymes Play in Toxicology?
Metabolic enzymes present in tissues play a significant role in the detoxification and activation of toxicants. The liver, for example, is rich in enzymes that can transform lipophilic toxicants into more hydrophilic compounds, facilitating their excretion. However, some metabolic reactions can also convert non-toxic compounds into toxic metabolites, highlighting the dual role of metabolism in toxicology.
