What Role Do Metabolism and Excretion Play in Toxicology?
Metabolism and excretion are critical factors in determining the toxicity of synthetic chemicals. Metabolism involves the biochemical transformation of substances, often rendering them more water-soluble for easier excretion. However, some metabolites can be more toxic than the parent compound. Excretion processes, through urine, feces, or sweat, help eliminate these substances from the body, reducing their toxic effects.
