What Role Does Osmotic Pressure Play in Drug Action and Toxicity?
Many drugs and chemicals exert their effects by altering osmotic pressure. For example, diuretics increase urine production by affecting osmotic gradients in the kidneys. In the context of toxicity, the disruption of osmotic pressure can lead to adverse effects. Mannitol, an osmotic diuretic, is used to reduce intracranial pressure in cases of brain edema, but excessive use can lead to electrolyte imbalances and dehydration.
